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. 2019 Jun 26;10:803. doi: 10.3389/fphys.2019.00803

TABLE 2.

Histology parameters obtained in the rabbits ventilated with physiological variable ventilation (PVV), mathematically variable ventilation (MVV), pressure-controlled mode (PCV), and pressure controlled mode with regular sighs (PCS) at positive expiratory pressure (PEEP) levels of 6 and 9 cmH2O.

MP groups
HP groups
PVV MVV PCV PCS PVV MVV PCV PCS
Lung injury score 0.87 (0.076) 0.88 (0.072) 0.83 (0.072) 0.88 (0.171) 0.89 (0.069) 0.87 (0.034) 0.86 (0.084) 0.87 (0.042)
Global aeration score 0.67 (0.063) 0.67 (0.042) 0.65 (0.068) 0.67 (0.000) 0.65 (0.021) 0.65 (0.021) 0.67 (0.031) 0.65 (0.021)
Average aeration per FOV 0.65 (0.060) 0.63 (0.031) 0.64 (0.064) 0.63 (0.047) 0.65 (0.016) 0.65 (0.021) 0.65 (0.036) 0.63 (0.029)
Hemorrhage score 1.67 (0.66) 1.75 (0.47) 1.15 (0.29) 1.34 (0.42) 1.27 (0.28) 1.44 (0.50) 1.22 (0.155) 1.16 (0.234)
Alveolar septal thickening (oedema) score 0.61 (0.73) 0.71 (0.31) 0.40 (0.25) 0.56 (0.63) 0.68 (0.17) 0.75 (0.31) 0.35 (0.48) 0.50 (0.30)
Wet-to-dry lung weight ratio 10.03 (4.67) 11.15 (1.49) 8.87 (1.82) 10.54 (1.97) 10.09 (1.00) 9.92 (0.69) 10.12 (1.38) 10.07 (1.38)

Values displayed as group median (interquartile range). No statistically significant differences were observed. FOV, field of view; Lung injury score is a continuous variable interpreted between 0 (no injury) and 1 (severe injury). Aeration scores categorized as 1/3, 1/2, or 2/3. Hemorrhage scores classified as 0 (none), 1 (light), 2 (moderate), or 3 (severe). Alveolar septal thickening score is classified as 0 (<2 per FOV), 1 (2–4 per FOV), or 2 (>4 per FOV).