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. 2019 Jul;60(8):2787–2799. doi: 10.1167/iovs.19-26951

Figure 1.

Figure 1

LHX4 is present in early cone photoreceptors during chick retinal development. Large: maximum-intensity projection Z-stacks; small: single planes of the same Z-stacks. (A) Average transcripts per million (TPM) of genes between cone/HC progenitors and other early retinal progenitors. Highlighted in green are genes 1.5-fold enriched in cone/HC progenitors and highlighted in yellow are transcription factors. (B) TPM values for LHX4 in cone/HC progenitors and other early retinal progenitors. (C) Cross section of E6 chick retina imaged for LHX4, RXRG, and OTX2. Higher magnification: a single z-plane with marked LHX4+/OTX2+ (white arrow) or LHX4+/OTX2+/RXRG+ cell (yellow arrow). (D) Cross section of E10 chick retina imaged for LHX4 and RAXL. Higher magnification: a single z-plane with marked LHX4+/RAXL+ (white arrow) or LHX4+/RAXL− cell (yellow arrow). (E) Cross section of E10 chick retina imaged for LHX4 and MAFA. Higher magnification: a single z-plane with marked LHX4+/MAFA− (white arrow) or LHX4−/MAFA+ cell (yellow arrow). Scale bar represents 50 μm.