Table 1.
Patient characteristics categorized by BMI.
| Overall | Underweight (BMI <18.5) | Normal weight (BMI 18.5-25.0) | Overweight (BMI 25.0-30.0) | Obese (BMI >30) | p-valuea | |
|---|---|---|---|---|---|---|
| N | 909 | 73 (7.7%) | 409 (45.3%) | 285 (31.4%) | 142 (15.6%) | |
| Age (y), median (IQR) | 72 (57-83) | 70 (56-85) | 74 ( 57-84) | 75 (60-83) | 69 (55-79) | 0.211 |
| Fever (>38°C), n (%) | 633 (69.6) | 50 (68.5) | 286 (69.9) | 205 (71.9) | 92 (64.8) | 0.438 |
| Cough | 335 (36.9) | 33 (45.2) | 143 (35.0) | 108 (37.9) | 51 (35.9) | 0.604 |
| Median duration of admission (d) , median (IQR) | 5 (3-13) | 7 (3-12) | 5 (2-11) | 5 (3-13) | 6 (3-12) | 0.185 |
| Female, n (%) | 431 (47.4) | 32 (43.8) | 213 (52.0) | 123 (43.2) | 63 (44.4) | 0.560 |
| Current smoker, n (%) | 227 (25.0) | 18 (24.7) | 110 (26.9) | 74 (26.0) | 25 (17.6) | 0.398 |
| Cardiovascular disease, n (%) | 261 (28.7) | 13 (17.8) | 110 (26.9) | 76 (26.7) | 32 (22.5) | 0.380 |
| Cerebrovascular disease, n (%) | 103 (11.3) | 8 (11.0) | 43 (10.5) | 32 (11.2) | 20 (14.1) | 0.857 |
| Hypertension, n (%) | 211 (23.2) | 12 (16.4) | 85 (20.8) | 74 (26.0) | 40 (28.2) | 0.188 |
| Type II diabetes, n (%) | 185 (20.4) | 9 (12.3) | 76 (18.6) | 65 (22.8) | 35 (24.6) | 0.128 |
| Scores of APACHE II | 18 (8∼31) | 19 (9∼28) | 17 (8∼31) | 21 (8∼29) | 18 (9∼28) | 0.235 |
| Laboratory findings at admission, median (IQR) | ||||||
| WBC | 12.2 (8.9-16.3) | 13.8 (11.3-17.8) | 12.5 (8.7-17.6) | 12.3 (9.2-15.9) | 11.4 (9.0-16.2) | 0.162 |
| CRP (mg/L) | 154.4 (74.0-237.0) | 132.1 (67.3-217.9) | 151.6 (75.8-243.5) | 157.3 (74.5-245.0) | 189.3 (97.3-278.2) | 0.045 |
| PCT (ug/L) | 0.52 (0.16-3.31) | 0.61 (0.22-3.89) | 0.54 (0.17-3.24) | 0.59 (0.21-3.01) | 0.41 (0.15-3.42) | 0.982 |
| TNF-α (pg/mL) | 13.5 (11.2-20.5) | 15.6 (13.43-21.6) | 12.5 (10.33-17.03) | 13.5 (11.42-21.34) | 14.2 (11.8-19.8) | 0.102 |
| IL-1 (ng/L) | 27.8 (13.5-30.9) | 25.6 (12.3-30.2) | 27.2 (13.6-29.9) | 26.1 (12.9-31.4) | 30.4 (16.7-34.8) | 0.658 |
| CAP severity, n (%) | ||||||
| PSI grade 1 | 109 (12.0) | 9 (12.3) | 54 (13.2) | 31 (10.9) | 15 (10.6) | 0.924 |
| PSI grade 2 | 150 (16.5) | 12 (16.4) | 70 (17.1) | 44 (15.4) | 24 (16.9) | 0.989 |
| PSI grade 3 | 165 (18.2) | 15 (20.5) | 74 (18.1) | 55 (19.3) | 21 (14.8) | 0.749 |
| PSI grade 4 | 331 (36.4) | 24 (32.9) | 143 (35.0) | 106 (37.1) | 58 (40.8) | 0.900 |
| PSI grade 5 | 154 (16.9) | 13 (17.8) | 68 (16.6) | 49 (17.2) | 24 (16.9) | 0.813 |
| Mortality, n (%) | ||||||
| 30 d | 43 (4.7) | 2 (2.7) | 19 (4.6) | 17 (6.0) | 5 (3.5) | 0.676 |
| 6 m | 76 (8.4) | 4 (5.5) | 40 (9.8) | 25 (11.6) | 7 (4.9) | 0.350 |
| 1 yr | 151 (14.9) | 11 (15.1) | 70 (17.1) | 59 (20.7) | 11 (7.7) | 0.072 |
a
Compared among the 4 groups.