Table 3.
Correlation between LPA2 expression and clinicopathological characteristics (n).
| Index | N=51 | LPA2 | Chi-square | P | |
|---|---|---|---|---|---|
| + (n=34) | − (n=17) | ||||
| Gender | 0.17 | 0.68 | |||
| Male | 47 | 32 | 15 | ||
| Female | 4 | 2 | 2 | ||
| Age (years) | 0.30 | 0.59 | |||
| <50 | 8 | 6 | 2 | ||
| ≥50 | 43 | 28 | 15 | ||
| Tumor location | 0.96 | 0.62 | |||
| Cardia | 28 | 17 | 11 | ||
| Body of stomach | 10 | 7 | 3 | ||
| Pylorus | 13 | 10 | 3 | ||
| Lauren type | 5.46 | 0.02 | |||
| Intestinal type | 42 | 25 | 17 | ||
| Diffuse type | 9 | 9 | 0 | ||
| Vascular invasion | 5.16 | 0.02 | |||
| No | 38 | 22 | 16 | ||
| Yes | 13 | 12 | 1 | ||
| Lymph node metastasis | 7.76 | 0.01 | |||
| No | 28 | 14 | 14 | ||
| Yes | 23 | 20 | 3 | ||
| Clinical stage | 8.71 | 0.03 | |||
| I | 22 | 10 | 12 | ||
| II | 13 | 11 | 2 | ||
| III | 12 | 9 | 3 | ||
| IV | 4 | 4 | 0 | ||
| Invasion depth | 11.63 | 0.00 | |||
| Mucosa or submucosa | 11 | 3 | 8 | ||
| Muscularis | 10 | 6 | 4 | ||
| Serosa | 30 | 25 | 5 | ||
| Tumor diameter | 0.02 | 0.89 | |||
| ≤5 cm | 35 | 23 | 12 | ||
| >5 cm | 16 | 11 | 5 | ||
| Histological grade | 0.00 | 0.96 | |||
| Well | 16 | 4 | 12 | ||
| Moderate | 16 | 13 | 3 | ||
| Poor | 19 | 17 | 2 | ||
LPA2 – lysophosphatidic acid receptor-2.