Table 2.
Comparison of comorbidities according to the clustering groups
| Characteristics | ACO | Mild | Moderate | Severe | p-value |
|---|---|---|---|---|---|
| No | 196 | 313 | 345 | 341 | |
| Hypertension | 87 (44.4) | 124 (39.6) | 136 (39.4) | 126 (37.0) | 0.410 |
| Asthma | 68 (34.7) | 85 (27.2) | 130 (37.7) | 117 (34.3) | 0.035 |
| Diabetes mellitus | 38 (19.4) | 62 (19.9) | 59 (17.1) | 44 (12.9) | 0.083 |
| GERD | 32 (16.3) | 28 (9.0) | 37 (10.8) | 23 (6.7) | 0.004 |
| Allergic rhinitis | 29 (14.9) | 33 (10.6) | 35 (10.3) | 38 (11.4) | 0.393 |
| Hyperlipidemia | 26 (13.3) | 53 (17.0) | 35 (10.4) | 32 (9.3) | 0.014 |
| Myocardial infarction | 11 (5.6) | 22 (7.1) | 19 (5.5) | 8 (2.3) | 0.043 |
| Osteoporosis | 10 (5.1) | 17 (5.4) | 22 (6.4) | 11 (3.2) | 0.289 |
| Atopic dermatitis | 9 (4.6) | 15 (4.8) | 8 (2.4) | 1 (0.4) | <0.001 |
| Heart failure | 6 (3.1) | 8 (2.6) | 13 (3.8) | 10 (2.9) | 0.840 |
| Periperal vascular disease | 4 (2.0) | 5 (1.6) | 6 (1.7) | 5 (1.5) | 0.958 |
| Thyroid disease | 2 (1.0) | 10 (3.2) | 7 (2.1) | 11 (3.2) | 0.331 |
| IBD | 1 (0.5) | 3 (1.0) | 0 (0.0) | 5 (1.5) | 0.107 |
Note: Data are presented as number (%).
Abbreviations: GERD, gastroesophageal reflux disease; IBD, inflammatory bowel disease.