Table 1.
Characterization of lipid-polymer hybrid nanoparticles (LPHNs) (mean ± SD, n=3)
| Characteristics | Particle size (nm) | PDI | Zeta potential (mV) | DL (%) | EE (%) | ||
|---|---|---|---|---|---|---|---|
| DOX | GA | DOX | GA | ||||
| HA-DOX/GA-LPHNs | 165.7±4.6 | 0.167±0.021 | −41.3±2.8 | 10.2±0.9 | 5.3±0.5 | 88.9±3.7 | 85.6±3.5 |
| DOX/GA-LPHNs | 131.2±3.5 | 0.129±0.011 | −30.5±2.3 | 13.5±1.1 | 6.4±0.4 | 86.9±3.4 | 84.7±3.9 |
| HA-DOX-LPHNs | 162.6±4.1 | 0.151±0.019 | −40.5±2.9 | 10.3±0.8 | N/A | 87.4±3.3 | N/A |
| HA-GA-LPHNs | 164.1±4.3 | 0.133±0.017 | −39.7±2.6 | N/A | 5.1±0.3 | N/A | 86.1±3.1 |
| HA-LPHNs | 161.9±3.9 | 0.141±0.012 | −38.9±3.1 | N/A | N/A | N/A | N/A |