Table 2.
IC50 values of doxorubicin (DOX) and gallic acid (GA) when different ratios were used in hyaluronic acid-DOX/GA-lipid-polymer hybrid nanoparticles (mean ± SD, n=3)
DOX/GA ration (w/w) | IC50 of DOX (μM) | IC50 of GA (μM) |
---|---|---|
10:1 | 9.73±0.82 | 0.97±0.12 |
5:1 | 2.95±0.33 | 0.59±0.09 |
2:1 | 0.46±0.06 | 0.23±0.05 |
1:1 | 1.03±0.17 | 1.03±0.19 |
1:2 | 1.79±0.22 | 3.58±0.49 |
1:5 | 2.18±0.37 | 10.92±0.86 |