Figure 2.
Survival, bacterial growth, and cytokine expression following SPH treatment. Sham‐, burn‐, or burn+SPH‐treated mice were inoculated with 1 × 106 CFU PA 24 h after injury. (A) Kaplan‐Meier survival curve is shown after inoculation (n = 12–14 mice/group). (B) Four hours after infection, BAL was harvested and CFUs quantified. (n = 8‐14 mice/group). (C) SPH was applied to PA in an in vitro assay and the CFUs enumerated. BALf was harvested 4 h after inoculation and IL‐6 (D) and ‐10 (E) were measured (n = 4–7 mice/group). *P < 0.05 vs. sham, # P < 0.05 vs. burn + SPH.