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The complement system is not essential for control of B. hermsii. Representative plot of bacterial numbers in blood of B. hermsii‐infected wild‐type, C1qa −/−, and C3 −/− mice throughout 13‐day infections, as determined by dark‐field microscopy. The limit of detection of B. hermsii in blood was 102 bacteria/μl. There were no significant differences in peak bacteremia levels for any mice (P>0.1 by one‐way ANOVA). See Supplemental Figure 2 for data about all experimental animals.
