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. 2016 Jun 2;100(2):305–314. doi: 10.1189/jlb.4RU0216-084R

Figure 3.

Figure 3

Proposed mechanism of MAIT cell restitution in the colon and blood following the initiation of ART. MAIT cells are lost from the colon during HIV infection [43], although the rate of MAIT loss may be markedly slower than it is in blood MAIT [42]. MAIT cell frequency is reconstituted in the colon following the initiation of ART [43]. Reconstitution may occur because of decreased mucosal inflammation and may be due to recruitment of MAIT cells from other compartments, such as the blood, or from local proliferation. MAIT‐cell reconstitution after initiation of ART is slower in blood than it is in the colon.