Figure 3.

Classification results. Ellipses represent clusters resulting from cluster-center analysis based on the APCIdx. Red ellipse represents the cluster of affected patients; blue ellipse represents the cluster of unaffected patients. Filled symbols represent individual APCIdxs; open symbols represent cluster centers (final cluster centers c1 = 0.13, c2 = −0.2). Noteworthy, a separation of affected and unaffected patients based on the performance of the healthy control subjects led to the same classification. Range of healthy controls from 25 lower to 75 upper percentile outlined as green box.