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. 2014 May 7;34(19):6679–6686. doi: 10.1523/JNEUROSCI.0513-14.2014

Figure 6.

Figure 6.

Acidification opens TRP irreversibly. A, A shift from pH 7.15 to 6.4 opens TRP in the double mutant inaE;trpl, staying open after shifting back to pH 7.15 (n = 8). B, TRP opened by acidification could not be closed by ATP (n = 5).