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Model for Drosophila phototransduction. Light-activated rhodopsin (Rh) couples to a G-protein (GP) activating PLC, which cleaves PIP2 into IP3, DAG, and a proton. DAG opens TRP and TRPL, allowing an inward cationic current generating a depolarizing receptor potential, while PIP2 and H+ have no relevant role in this process. The genes encoding for the corresponding proteins are denoted in italics.
