Figure 2.

Effects of ChABC injections into the amygdala on the retrieval, reconsolidation, and retention of morphine-induced CPP. A, C, Timeline of experimental procedure. B, D, ChABC (0.01 U/side) microinfusions into the BLA or CeA 1 d after the postconditioning test had no effect on the retention (B), retrieval, or reconsolidation (D) of morphine-induced CPP. No significant difference was found in the retention, retrieval, or reconsolidation test between the ChABC group and vehicle group. The data are expressed as the mean ± SEM preference scores in seconds (time spent in the morphine-paired chamber minus time spent in the saline-paired chamber) during the CPP tests (n = 7–8 per group). Post-C, Postconditioning test; Post-T1, postextinction test 1; Post-T2, posttreatment test 2.