Figure 8.

Effects of intra-BLA ChABC injections and extinction training on PNNs and plasticity-related protein levels. A, Timeline of experimental procedure. B, C, Representative WFA-positive PNN immunostaining in the BLA and CeA under different experimental conditions (left column). Scale bar, 100 μm. ChABC infusions into the BLA significantly decreased WFA-positive PNNs in the BLA but not CeA (right column). D, Effect of the different manipulations on plasticity-related protein levels in the BLA. The data are expressed as mean ± SEM percentage differences from the vehicle + no extinction group. *p < 0.05 vs vehicle group; #p < 0.05 vs vehicle + extinction and ChABC + no extinction groups (n = 4–7 per group).