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BDNF signaling within BLA-IL circuit mediating CTA extinction. During CTA extinction, BLA receives information that induces the secretion of BDNF and subsequent activation of TrkB and BDNF synthesis. Then the activated TrkB signaling in the BLA is rapidly transmitted to the IL, which triggers BDNF secretion and synthesis in the IL. The BDNF signaling activation in the IL finally mediates CTA extinction.
