Figure 4.

Drug-induced modulation of TEPs. TEPs were recorded before (Pre, blue) and after (Post, red) intake of a single oral dose of alprazolam, zolpidem, or placebo (Experiment 1, A), and diazepam, baclofen, or placebo (Experiment 2, B). Whereas alprazolam increased the N45 and reduced the N100 amplitude, zolpidem increased the N45 only. Diazepam increased the N45 and decreased the N100 similarly to alprazolam, whereas baclofen increased the N100. Black bars underneath represent significant drug-induced changes in TEPs. The baseline was corrected between −500 ms and −100 ms. To illustrate drug-induced changes of TEP components, representative channels were chosen for each drug condition. Shades represent ± SEM. For further information see also Figure 3.