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. 2014 Jun 11;34(24):8139–8150. doi: 10.1523/JNEUROSCI.5200-13.2014

Figure 9.

Figure 9.

Cx3cr1 deficiency leads to additional loss of photoreceptor function in rd10 retinas. Cx3cr1 deletion did not affect retinal function in WT retinas. Scotopic and photopic ERG responses are indistinguishable between Cx3cr1GFP/GFP mice and Cx3cr1+/GFP mice (blue curves in A–C and bars in D–F). Scotopic and photopic ERG a-wave amplitudes are virtually comparable between rd10 mice with or without Cx3cr1 deletion (black curves and bars). However, scotopic and photopic ERG b-wave amplitudes are significantly smaller in rd10 mice with Cx3cr1 deletion, compared with rd10 mice without Cx3cr1 deletion (black curves in A–C and bars in D–F). Values are means and SDs. n = animal numbers; *p < 0.05 and **p < 0.01.