Table 3.
Total gray matter volume and hippocampal volume and microstructure of subjects before and after the intervention/control period
| Parameter | Resveratrol |
Placebo |
||||
|---|---|---|---|---|---|---|
| Pre | Post | pa | Pre | Post | pa | |
| Total gray matter volume (cm3) | 576.2 ± 52.8 | 575.3 ± 54.7 | 0.64 | 568.6 ± 45.2 | 566.7 ± 43.0 | 0.23 |
| HCant, left | ||||||
| Volume (cm3) | 2.28 ± 0.35 | 2.26 ± 0.34 | 0.57 | 2.21 ± 0.28 | 2.21 ± 0.26 | 0.87 |
| MD (m2/s) | 1.17 ± 0.08 | 1.18 ± 0.07 | 0.50 | 1.15 ± 0.06 | 1.16 ± 0.08 | 0.30 |
| HCpost, left | ||||||
| Volume (cm3) | 1.59 ± 0.25 | 1.58 ± 0.24 | 0.74 | 1.54 ± 0.21 | 1.56 ± 0.20 | 0.24 |
| MD (m2/s) | 1.08 ± 0.10 | 1.09 ± 0.09 | 0.71 | 1.09 ± 0.09 | 1.09 ± 0.11 | 0.50b |
| HCant, right | ||||||
| Volume (cm3) | 2.32 ± 0.26 | 2.29 ± 0.29 | 0.25 | 2.29 ± 0.19 | 2.33 ± 0.19 | 0.32 |
| MD (m2/s) | 1.11 ± 0.07 | 1.12 ± 0.07 | 0.43 | 1.13 ± 0.08 | 1.11 ± 0.09 | 0.41 |
| HCpost, right | ||||||
| Volume (cm3) | 1.65 ± 0.21 | 1.63 ± 0.20 | 0.08 | 1.63 ± 0.17 | 1.63 ± 0.23 | 0.96 |
| MD (m2/s) | 1.05 ± 0.10 | 1.07 ± 0.08 | 0.58 | 1.05 ± 0.08 | 1.06 ± 0.11 | 0.62 |
Data are given as mean ± SD. Microstructure was measured using MD estimates.
aPaired t test except
bWilcoxon-signed-rank-test.