Table 5.
Fasting serum parameters, anthropometric measures, vascular parameters, physical activity, and mood of subjects before and after the intervention/control period
| Parameter | Resveratrol |
Placebo |
||||
|---|---|---|---|---|---|---|
| Pre | Post | p | Pre | Post | p | |
| HbA1c, %a | 5.83 ± 0.2 | 5.70 ± 0.2 | 0.007e | 5.85 ± 0.3 | 5.88 ± 0.3 | 0.53e |
| Glucose (mg/dl) | 90.7 ± 6 | 89.9 ± 8.1 | 0.56e | 93.8 ± 8.3 | 93.5 ± 9.2 | 0.86e |
| Insulin (mU) | 7.8 ± 3.4 | 9.8 ± 6.3 | 0.046f | 9.2 ± 4.5 | 8.5 ± 3.4 | 0.47f |
| Total cholesterol (mg/dl) | 221.5 ± 33.1 | 231.4 ± 36.8 | 0.008e | 223.4 ± 33.4 | 220.6 ± 36.4 | 0.53e |
| LDL-to-HDL ratio | 2.5 ± 1.1 | 2.7 ± 1.5 | 0.06e | 2.5 ± 0.6 | 2.5 ± 0.7 | 0.76e |
| Triacylglycerides (mg/dl) | 103.8 ± 42.4 | 115 ± 53.5 | 0.18e | 115.7 ± 44.7 | 110.0 ± 50.5 | 0.47e |
| Leptin (ng/ml) | 9.4 ± 7.8 | 16.9 ± 12.5 | 0.001f | 15.0 ± 12.7 | 10.9 ± 10.2 | 0.031f |
| BDNF (pg/ml) | 4082 ± 1608 | 3994 ± 1231 | 0.82e | 4062 ± 854 | 4140 ± 1100 | 0.65f |
| IGF-1 (ng/ml) | 132.5 ± 34 | 134.4 ± 38 | 0.63e | 140.3 ± 45 | 136.0 ± 36 | 0.52e |
| TNF-alpha (pg/ml) | 10.3 ± 2.3 | 8.0 ± 1.8 | <0.001e | 15.7 ± 15.3 | 9.5 ± 2.1 | 0.006f |
| Interleukin 6 (pg/ml) | 2.9 ± 1.2 | 2.0 ± 0.2 | 0.002f | 7.9 ± 19.8 | 4.0 ± 8.9 | 0.021f |
| hsCRP (pg/ml) | 1.3 ± 1.3 | 1.5 ± 1.4 | 0.18f | 2.7 ± 3.2 | 6.2 ± 19.3 | 0.86f |
| Body fat (%)a | 30 ± 7.6 | 28.8 ± 7.6 | 0.082e | 30.0 ± 8.0 | 30.9 ± 7.2 | 0.20f |
| Weight, kg | 81.8 ± 9.8 | 81.3 ± 10 | 0.16e | 83 ± 7.7 | 83 ± 7.6 | 0.98e |
| Body mass index, kg/m2 | 27.4 ± 1.9 | 27.2 ± 1.9 | 0.15f | 27.7 ± 1.6 | 27.7 ± 1.6 | 0.86e |
| CIMT left (μm)b | 672.3 ± 136 | 681.8 ± 110 | 0.80e | 654.3 ± 115 | 658.2 ± 124 | 0.27e |
| CIMT right (μm)c | 632.5 ± 103 | 663.0 ± 99 | 0.34e | 651.5 ± 122 | 645.2 ± 106 | 0.06e |
| Systolic blood pressure (mm Hg)d | 141.2 ± 18 | 135.3 ± 15 | 0.17e | 139.3 ± 16 | 139 ± 15 | 0.94e |
| Diastolic blood pressure (mm Hg)d | 92.7 ± 9 | 87.5 ± 11 | 0.036e | 88.0 ± 11 | 86.6 ± 12 | 0.60e |
| Physical activity (kcal/week2) | 5646 ± 2829 | 5797 ± 1089 | 0.86e | 4946 ± 3850 | 5086 ± 4670 | 0.52f |
| Positive PANAS scored | 34.1 ± 6.0 | 32.0 ± 5.7 | 0.13e | 32.2 ± 6.5 | 31.4 ± 7.2 | 0.29e |
| Negative PANAS scored | 10.8 ± 1.5 | 11.2 ± 1.7 | 0.50f | 12.4 ± 3.2 | 11.8 ± 2.2 | 0.18f |
Significant changes are indicated by bolding the number. Data are given as mean ± SD.
aTwo subjects.
bThree subjects.
cFour subjects.
dOne subject excluded due to missing values.
ePaired t test.
fWilcoxon signed-rank test.