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. 2014 Jul 23;34(30):10034–10040. doi: 10.1523/JNEUROSCI.0715-14.2014

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Copyright © 2014 the authors 0270-6474/14/3410034-07$15.00/0

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Figure 1. — mHTT causes spindle misorientation. A, Measurement of the spindle angle α. STHdh^Q7/Q7 (Q7) and STHdh^Q111/Q111 (Q111) cells stained as indicated. B, C, Spindle angles of Q7, Q111 (B), and HeLa (C) cells. D, E, Spindle angles of Q7 (D) and Q111 (E) cells grown on micropatterns. Time-lapse pictures were used to measure the positioning of the metaphasic plate (H2B-mCherry). Scale bars, 10 μm. Error bars indicate SEM. **p < 0.01 (unpaired, one-tailed t test). ***p < 0.001 (unpaired, one-tailed t test).