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Lenti-CREB-SUMO1 fusion vector transduction enhances spatial learning and memory and increases CREB SUMOylation. Effects of Lenti-CREBWT and Lenti-CREB-SUMO1 fusion vector transduction to the rat CA1 area on spatial acquisition (A), probe trial performance (B), and CREB SUMOylation (C) are shown. The quantified result of CREB SUMOylation is shown in D. n = 8 each group. Data are expressed as mean ± SEM. *p < 0.05; **p < 0.01; #p < 0.001.
