Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
IKKβ ablation inhibits NF-κB activation in primary cultured microglia. IKKβ protein (A, B; t test; n = 3 per group) and phosphorylated and total NF-κB p65 (C, D; t test; n = 3 per group) in the primary cultured microglial cell lysate derived from ikbkbfl/flCre+/− (IKKβko) and ikbkbfl/flCre−/− (IKKβwt) mice were detected and quantified with Western blotting. For NF-κB activation assays, IKKβ wt and ko microglia were activated with 10 μm oligomeric Aβ42 for 12 min.
