Figure 6.

Selective increase of Kv4.3 protein expression in DA SN neurons of A53T-SNCA mice. A, B, Confocal images of immunocytochemistry of DA SN and DA VTA neurons for TH (green, top) and Kv4.3 channel protein (red, bottom) in control (A) and A53T-SNCA (B) mice, respectively. Scale bar, 20 μm. C, D, Histogram showing intensity of Kv4.3 immunosignals for TH-positive ROIs, in DA SN (C) and DA VTA (D) neurons in control (black) and A53T-SNCA (red) mice, respectively. E, F, Comparison of mean TH-colocalized Kv4.3 immunosignals from DA SN (E) and DA VTA (F) neurons in control and A53T-SNCA mice; **p > 0.005; ns, Mann–Whitney test.