Table 1.
Histological grades (HG) and neuronal density (ND) in the hippocampal CA1.
| Group | HG |
ND | |||
|---|---|---|---|---|---|
| 0 | I | II | III | ||
| Sham | 6 | 202.33 ± 10.39 | |||
| I/R | 5 | 1 | 85.00 ± 5.06∗ | ||
| I/R + Pir | 1 | 5 | 54.00 ± 4.98∗# | ||
| I/R + CYC | 1 | 5 | 50.33 ± 5.65∗# | ||
| ISO | 6 | 145.00 ± 7.48∗# & |
|||
| ISO + Pir | 3 | 3 | 102.67 ± 6.62∗& |
||
| ISO + SIS3 | 3 | 3 | 96.83 ± 7.41∗& |
||
| ISO + CYC | 4 | 2 | 99.50 ± 9.57∗& |
||
| ISO + Pir + CYC | 2 | 4 | 72.67 ± 5.99∗&Δ |
||
The standard of HG: grade 0, no cell death; grade I, scattered cell death; grade II, mass cell death; grade III, almost complete cell death. ND represented the number of surviving pyramidal neurons per 1 mm length in the CA1 hippocampus. Data are shown as the mean ± SD (n = 3). ∗ P < 0.05 vs. Sham; # P < 0.05 vs. I/R; P < 0.05 vs. I/R + Pir; & P < 0.05 vs. I/R + CYC; Δ P < 0.05 vs. ISO.