Table 4.
Mean body weight (grams) showing normal body growth in GluN2B+/− and GluN2D−/− mutants even after ION transectiona
| Age | GluN2B+/+ | GluN2B+/− | GluN2D+/+ | GluN2D−/− |
|---|---|---|---|---|
| Naive mice | ||||
| P0 | 1.20 ± 0.02 | 1.22 ± 0.02 | 1.23 ± 0.01 | 1.23 ± 0.01 |
| P4 | 2.50 ± 0.07 | 2.50 ± 0.05 | 2.49 ± 0.04 | 2.50 ± 0.04 |
| P12 | 6.09 ± 0.05 | 6.07 ± 0.06 | 6.07 ± 0.05 | 6.08 ± 0.06 |
| ION lesioned mice | ||||
| P11 (P3-lesion) | 5.87 ± 0.11 | 5.83 ± 0.08 | 5.91 ± 0.09 | 5.85 ± 0.11 |
| P11 (sham) | 5.91 ± 0.08 | 5.88 ± 0.11 | 5.84 ± 0.12 | 5.90 ± 0.10 |
| P13 (P5-lesion) | 6.33 ± 0.13 | 6.27 ± 0.18 | 6.25 ± 0.18 | 6.29 ± 0.19 |
| P13 (sham) | 6.31 ± 0.11 | 6.25 ± 0.17 | 6.28 ± 0.15 | 6.31 ± 0.11 |
aIn naive mice, the mean body weight shows no significant differences between control and mutant mice. In ION transection experiments, no significant differences were found between lesioned and sham-operated mice. Data are presented as mean ± SEM. p > 0.05 for each (one-way ANOVA with Bonferroni post hoc comparisons). n = 12 for each group.