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. 2014 Feb 19;34(8):2884–2897. doi: 10.1523/JNEUROSCI.1675-13.2014

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Copyright © 2014 the authors 0270-6474/14/342884-14$15.00/0

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Figure 8. — Aβ40 monomer concentration is unchanged between the AD and aged controls in Cohort 1 and 2 (A and C, respectively) while Aβ42 values are reduced by twofold in the AD samples (B, Cohort 1, p < 0.002; D, Cohort 2, p < 0.001; geometric mean and 95% CI). A Cohort 2 subset was analyzed because of limited CSF volumes available. The correlation between Aβ40 and oligomers was significant for the AD CSF (r = 0.49, p = 0.03; ■), but not aged control CSF (E; □). Correlation between Aβ42 and oligomers was not significant for either group (F; AD, ♦; control, ◊).