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. 2014 Feb 5;34(6):2191–2202. doi: 10.1523/JNEUROSCI.0862-13.2014

Figure 6.

Figure 6.

Wnt activators rescue memory impairment in adult APP/PS1 mice. A–C, Behavioral performance of APP/PS1 mice treated with WASP-1 (n = 7), FOXY-5 (n = 6), and control (n = 7) evaluated by the novel object recognition test. A, Total object exploration time during acquisition memory phase of the test, showing no significant differences (n.s.) among groups. B, Preference index for the novel object during retention memory phase of the test. Comparison among control WT mice and the APP/PS1 groups. C, Comparison of preference index for the novel object between WT and APP/PS1 mice treated with WASP-1 or FOXY-5 during retention memory phase of the test. Tg, Transgenic APP/PS1 mice; Ct, control.