Table 2.

Euglycemic Hyperinsulinemic Clamp Data

	Control	VFA Only	FL Only	VFA Plus FL	P a
%Reduction of EGP/SSSI at first step, %/μU·mL−1	3.6 ± 1.0	3.7 ± 0.8	2.6 ± 0.7	2.7 ± 1.2	0.006
Rd/SSSI at second step, mg/kg FFM·min−1/μU·mL−1	0.23 ± 0.07	0.21 ± 0.09	0.12 ± 0.04b	0.13 ± 0.04b	<0.001
%FFA suppression/insulin at first step, %/μU·mL−1	4.4 ± 1.0	3.9 ± 0.9	2.7 ± 0.7b,c	2.8 ± 1.0b	<0.001
MCRI at second step, mL/min per m2	551.7 ± 78.7	536.7 ± 125.4	478.9 ± 52.9	488.1 ± 77.4	0.080

Data are expressed as mean ± SD.

Abbreviations: SS_SI, steady-state serum insulin; EGP, endogenous glucose production; Rd, rate of disappearance.

^a P value for one-way ANOVA or Kruskal-Wallis analysis.

^b P < 0.05 for Tukey-Kramer or Games-Howel; vs control.

^c P < 0.05 for Tukey-Kramer or Games-Howel; vs VFA only.