Table 1.
Characteristics of the subjects with early-onset preeclampsia and normal pregnancy.
| Antepartum | 1 week postpartum | 6 weeks postpartum | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
Normal control (NC) |
Preeclampsia (PE) |
P-value |
Normal control (NC) |
Preeclampsia (PE) |
P-value |
Normal control (NC) |
Preeclampsia (PE) |
P-value | |
| No. of individuals | 51 | 48 | 17 | 35 | 11 | 18 | |||
| PREGNANT WOMEN PARAMETERS | |||||||||
| Age, years | 29.7 ± 4 | 32.2 ± 5.5 | 0.052 | 29.5 ± 3.8 | 33 ± 5.4 | 0.025 | 29.5 ± 2.9 | 33.8 ± 5.4 | 0.036 |
| Gestational weeks | 39.8 ± 1.3 | 31.2 ± 4.2 | < 0.001 | 39.4 ± 1.1 | 31.4 ± 4.9 | < 0.001 | 39.7 ± 0.8 | 33.3 ± 6.5 | 0.001 |
| Pre-preg. weight (kg) | 52.7 ± 6.5 | 56.9 ± 10.3 | 0.094 | 49.7 ± 7.8 | 59 ± 12.6 | 0.011 | 53.3 ± 8.4 | 51.6 ± 6.6 | 0.617 |
| Antenatal weight (kg) | 66 ± 7.8 | 69.1 ± 10.3 | 0.261 | 62.6 ± 9.5 | 67 ± 9.4 | 0.202 | 75.5 ± 9.9 | 63.6 ± 8.9 | 0.09 |
| Height (cm) | 158 ± 4.4 | 158 ± 4.9 | 0.676 | 158 ± 6 | 158 ± 6 | 0.629 | 158 ± 6 | 157 ± 4 | 0.841 |
| Pre-preg. BMI (kg/m2) | 21 ± 2.5 | 22.8 ± 4.1 | 0.072 | 19.9 ± 3 | 23.3 ± 4.2 | 0.009 | 21.5 ± 3.4 | 20.9 ± 2.6 | 0.662 |
| Fetal birth weight (kg) | 3.2 ± 0.3 | 1.4 ± 0.7 | < 0.001 | 3.2 ± 0.3 | 1.4 ± 0.9 | < 0.001 | 3.3 ± 0.3 | 1.7 ± 1.2 | 0.026 |
| Placenta weight (g) | 544 ± 69 | 334 ± 129 | 0.001 | 517 ± 54 | 339 ± 129 | 0.001 | 523 ± 30 | 320 ± 170 | 0.032 |
| CLINICAL AND IMMUNE INDEXES (ANTENATAL) | |||||||||
| i-FABP (pg/ml) | 1090.9 ± 652.9 | 1450.6 ± 732.4 | 0.068 | ||||||
| zonulin (ng/ml) | 19.6 ± 10.2 | 24.0 ± 39.7 | 0.553 | ||||||
| IL-6 (pg/ml) | 6.3 ± 17.7 | 18.9 ± 23.6 | 0.031 | ||||||
| LPS (pg/ml) | 2.9 ± 3.0 | 4.8 ± 4.8 | 0.036 | ||||||
| SBP (mmHg) | 114 ± 12 | 139 ± 18 | < 0.001 | ||||||
| DBP (mmHg) | 69 ± 10 | 91 ± 12 | < 0.001 | ||||||
| FBG (mmol/L) | 4.4 ± 0.4 | 4.6 ± 0.6 | 0.207 | ||||||
| HbA1C (%) | 5 ± 0.4 | 5.1 ± 0.5 | 0.597 | ||||||
| TG (mmol/L) | 2.6 ± 1 | 3.8 ± 1.8 | 0.009 | ||||||
| TCH (mmol/L) | 5.6 ± 1.3 | 6.4 ± 1.4 | 0.049 | ||||||
| HDL-C (mmol/L) | 1.9 ± 0.4 | 1.9 ± 0.4 | 0.652 | ||||||
| LDL-C (mmol/L) | 2.6 ± 0.9 | 3.1 ± 0.9 | 0.055 | ||||||
| HCT (%) | 35.6 ± 4.2 | 37.1 ± 3.9 | 0.145 | ||||||
| ALT (U/L) | 12 ± 14.6 | 18.5 ± 15.7 | 0.104 | ||||||
| AST (U/L) | 16.4 ± 6.6 | 21.8 ± 8.6 | 0.014 | ||||||
| CRE (umol/L) | 45.1 ± 7.2 | 62.3 ± 18.7 | < 0.001 | ||||||
The data for NC and PE were presented as mean ± SD. P-values were calculated by Student's t-test. BMI, body mass index; i-FABP, intestinal fatty acid binding protein; IL-6, interleukin 6; LPS, lipopolysaccharide; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; HbA1C, hemoglobin A1c; TG, triglyceride; TCH, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HCT, hematocrit; ALT, alanine aminotransferase; AST, glutamic oxaloacetic transaminase; CRE, creatinine.