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Pharmacokinetics of OXT peptide analogs in mice. (A and B) Sixteen-wk-old naive male C57BL/6 mice (n = 3 per group) received a single dose (1 mg/kg, IP) of OXT or OXTGly (A) or acylated-OXT or acylated-OXTGly (B). Plasma was collected at 0.5, 1, 3, 6, and 24 h after dosing via cardiac puncture. Circulating levels of each peptide were quantified by mass spectrometry analysis.
