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mg/kg Dose variations for mefloquine (MQ). The WHO recommendation on the 3-day fixed-dose artesunate-mefloquine regimen is to administer once daily 50 mg of MQ for those weighing 5–8 kg, 100 mg for 9–17 kg, 200 mg for 18–29 kg and 400 mg for those who weigh ≥30 kg. The horizontal dotted line represents the target MQ dose of 25 mg/kg. Since the dosing is based on weight bands, this leads to the saw-tooth dosing curves.
