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. 2019 Jun 28;9(6):e027604. doi: 10.1136/bmjopen-2018-027604

Table 4.

The appropriateness* of antimicrobial therapy†

Total
n=163
Site A
n=43
Site B
n=120
Appropriate 101 (62.0) 26 (60.6) 75 (62.5)
Inappropriate 62 (38.0) 17 (39.4) 45 (37.5)
Reasons for inappropriateness‡
 No infection 15 (9.2) 7 (16.3) 8 (6.7)
 Inappropriate dose or timing 14 (8.6) 9 (20.9) 5 (4.2)
 Inappropriate duration 2 (1.2) 0 (0.0) 2 (1.7)
 Inappropriate choice 10 (6.1) 0 (0.0) 10 (8.3)
 Inappropriate spectrum§ 27 (16.6) 2 (4.7) 25 (20.8)

*The appropriateness of antimicrobial therapy was determined by members of the infection control team of each hospital based on the results of microbial tests at the time of the survey, antibiograms of each hospital, and the Infectious Diseases Society of America Practical Guidelines.

†Values are shown as numbers of antimicrobial drugs, with the percentage of the total number of antimicrobial drugs in parenthesis according to the type of infections.

‡Antimicrobial drugs could be given for more than one reason.

§Antimicrobial therapy was considered inappropriate if there were alternative antimicrobial drugs that were equally effective and had narrower spectrum activity.