Table 5.
Selection of Acetylated Transcription Factors and Their Writers and Erasers
| PROTEIN NAME |
ACETYL-LYSINE | WRITER | ERASER | UNIPROT ID |
REFS |
|---|---|---|---|---|---|
| AR | K630, K632, K633 | KAT2B, KAT3A, KAT3B, KAT5 | KDAC1, KDAC7 | P10275 | 362-365 |
| ATM | K3016 | KAT5 | Unknown | Q13315 | 52, 366 |
| BCL6 | K379 | KAT3B | Unknown | P41182 | 367 |
| BMAL1 | K537 | KAT13D | SIRT1 | 000327 | 101, 368 |
| CDK9 | K44, K48 | KAT2A, KAT2B, KAT3B | KDAC3, SIRT2 | P50750 | 369-372 |
| ChREBP | K672 | KAT3B | SIRT1 | Q9NP71 | 373, 374 |
| CREB | K91, K94, K136 | KAT3A, KAT3B | SIRT1, KDAC8 | P16220 | 375, 376 |
| CRTC2 | K628 | KAT3A, KAT3B | SIRT1 | Q53ET0 | 377 |
| CycT1 | K380, K386, K390, K404 | KAT3B | KDAC1, KDAC3 | 060563 | 315, 378, 379 |
| E2F1 | K117, K120, K125 | KAT2A, KAT2B, KAT3B | HDAC1 | Q01094 | 380-382 |
| EKLF | K270, K284 | KAT3A, KAT3B | Unknown | Q13351 | 383, 384 |
| ERα | K226, K268, K299, K302, K303 | KAT3A | SIRT1 | P03372 | 385-387 |
| Foxo1 | K242, K245, K248, K262, K265, K274 | KAT3B | SIRT1, SIRT2, SIRT3 | Q12278 | 379-393 |
| Foxp3 | K31, K327, K263, K268 | KAT3B, KAT5 | KDAC7, KDAC9, SIRT1 | Q9BPZS1 | 50, 394-396 |
| FXR | K217 | KAT3B | SIRT1 | Q96RI1 | 397, 398 |
| GABPB1 | K69, K340, K369 | KAT3B | SIRT7 | Q06547 | 399 |
| GATA1 | K158, K246, K252,K312 | KAT3A, KAT3B | KDAC5 | P15976 | 400-403 |
| HIF1α | K10, K11, K12, K19, K21, K709 | KAT2B, KAT3B | KDAC1, KDAC4, SIRT1, SIRT2 | Q16665 | 404-408 |
| HIF2α | K385, K685, K741 | KAT3A | SIRT1 | Q99814 | 409, 410 |
| HMG17 | K2 | KAT2B | Unknown | P05204 | 411 |
| IFNαR2 | K399 | KAT3A | Unknown | P48551 | 412 |
| Myc | K143, K148, K157, K275, K317, K323, K371 | KAT2B, KAT3B, KAT5 | SIRT1, SIRT2 | P01106 | 315, 413-416 |
| Notch 1 | K1764, K1770, K1771, K1772, K1785, K1935, K2050, K2068, K2146, K2147, K2150, K2154, K2161, K2164 | KAT2B, KAT3B | SIRT1 | P46531 | 417 |
| p53 | K120, K321, K373, K381, K382 | KAT6A, KAT3B | KDAC1, SIRT1, SIRT2 | P04637 | 315,418-422 |
| PAF53 | K373 | KAT2B | SIRT7 | Q9GZS1 | 423 |
| PRLR | K277, K339, K412, K456, K466, K472, K505, K514, K517, K526, K533, K536, K590, K601 | KAT3A | KDAC6, SIRT2 | P15471 | 424 |
| Pygo2 | K11, K43, K44, K47 | KAT3A, KAT3B | Unknown | Q9BRQ0 | 425 |
| RelA | K122, K123, K218, K221, K310, K314, K315 | KAT2B, KAT3A, KAT3B | KDAC3, SIRT1, SIRT2 | Q04206 | 426-430 |
| Rb | K873, K874 | PCAF | SIRT1 | P06400 | 431 |
| RORy | K69, K81, K99, K112 | KAT3B | KDAC1, SIRT1 | P51449 | 432, 433 |
| RPB1 | K1888, K1909, K1916, K1923, K1937, K1958, K1972, K1986 | KAT3B | Unknown | P24928 | 434, 435 |
| SMAD7 | K64, K70 | KAT3B | KDAC1, KDAC3, KDAC5, KDAC6 | O15105 | 436, 437 |
| Sp1 | K703 | KAT3B | Unknown | P08047 | 315, 438 |
| Sp3 | K551 | KAT3B | Unknown | Q02447 | 439-441 |
| SREBPIc | K289, K309 | KAT3B | SIRT1 | P36956 | 442 |
| STAT2 | K390 | KAT3A | Unknown | P52630 | 412, 443 |
| STAT3 | K49, K87, K685 | KAT3A, KAT3B | KDAC1, KDAC2, KDAC3 | P40763 | 444-446 |
| STAT5b | K359, K694, K696, K701 | KAT3A | SIRT2, KDAC6 | P51692 | 424, 447 |
| HIV-1 Tat | K28, K50, K51 | KAT2A, KAT2B, KAT3B | SIRT1 | P04608, P04610 | 448-451 |
| UBF1 | K352 | KAT3A | Unknown | P17480 | 452 |
| YY1 | K173, K174, K178, K179, K180, K181 | KAT2B, KAT3B | KDAC1, KDAC2 | P25490 | 453 |