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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Biochem Pharmacol. 2018 Aug 16;156:302–311. doi: 10.1016/j.bcp.2018.08.017

Fig. 2.

Fig. 2.

AFM images and analysis of Pgp reconstituted in liposomes. The (A) AFM image and (B) cross-section (indicated by the dashed line in panel A) shows a void as well as a “large” and a “small” protrusion. (C) A representative 1 × 1 μm AFM image showing “large” protrusions (squares), “small” protrusions (circles) and aggregates (arrow). (D) AFM image and line scan of liposomes prepared without Pgp shows no discernable features. A downward step of approximately 40 Å (bottom right) is consistent with the presence of bilayer.