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. Author manuscript; available in PMC: 2019 Jul 3.
Published in final edited form as: Curr Opin Chem Biol. 2018 Apr 7;45:113–120. doi: 10.1016/j.cbpa.2018.03.017

Figure 2.

Figure 2

Schematic representation summarizing novel organic nUCAs. (a) Nanobubbles (NBs): perfluorocarbon gas-filled particles stabilized with a phospholipid shell (blue) and surfactant (purple). (b) Phase-change droplets (PCDs): perfluorocarbon droplets encapsulated in phospholipid or polymer-based (green) NPs. Phase-change of droplets occurs upon heating caused by ultrasound, near infrared, magnetic, radio-wave or microwave irradiation. (c) Gas-generating NPs (GGNPs): NPs containing a reactive functional group which produces gas at the site of interest. Reactive group can either be placed on the shell (Left) or inside the NPs (Right). Ca and Cb summarize the different mechanisms used to produce gas in GGNPs.