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. 2019 Jan 18;8:e36842. doi: 10.7554/eLife.36842

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© 2019, Breuer et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 14. — JCVI-syn1.0 has a doubling time of 66 min (blue; ‘×' markers), whereas JCVI-syn3A has a doubling time of 105 min (orange; ‘+' markers). Doubling times ( $t_{d}$ ) were calculated as described in Section 'Materials and methods', plotting fluorescence staining of cellular DNA vs. time, fitted by exponential regression curves. The regression curves for JCVI-syn1.0 and JCVI-syn3A have $R^{2}$ values of 0.9986 and 0.9976, respectively.