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Region of interest (ROI) setting on manual (a, b) and atlas-based (c, d) ALPS indexes. On the manual method, 5-mm-diameter spheres were placed on the projection and association fiber areas with reference to a color-coded FA map on each patient. On the atlas-based method, the labels of the projection and association fiber areas were defined by the labels of the ICBM DTI-81 Atlas. Values of coregistered maps were retrieved using these labels.
