Table 5.
RHM analysis conditioned on adding the top SNPs from GWAS to the model sequentially
Scenario | (SE) | (SE) | Logl | LRT |
---|---|---|---|---|
No condition | 0.030 (0.008) | 0.16 (0.02) | − 10644 | – |
Cond. on S1 | 0.028 (0.008) | 0.16 (0.02) | − 10643 | 2 |
Cond. on S1 + S2 | 0.026 (0.007) | 0.16 (0.02) | − 10642 | 4 |
Cond. on S1 + S2 + S3 | 0.026 (0.007) | 0.16 (0.02) | − 10644 | 0 |
Cond. on S1 + S2 + S3 + S4 | 0.023 (0.007) | 0.16 (0.02) | − 10641 | 6 |
Cond. on S1 + S2 + S3 + S4 + S5 | 0.020 (0.006) | 0.16 (0.02) | − 10637 | 14 |
Cond. on S1 + S2 + S3 + S4 + S5 + S6 | 0.019 (0.006) | 0.16 (0.02) | − 10636 | 16 |
GRMi and GRMc as in Table 4
S1: rs421630816; S2: rs424521894; S3: rs425769499; S4: rs416517011; S5: rs404837788; S6: rs413573644
Logl: log likelihood
SE: standard error