Table 3. HRs for risk of PD associated with MDD.

Variables		HR	95% CI	P value	HR	95% CI	P value
Overall
	Without MDD	1	-	-	1	-	-
	With MDD	14.728	9.494–22.849	< 0.001	3.872	2.361–6.349	< 0.001
Stratification by time
	Without MDD	1	-	-	1	-	-
	With MDD, 0	60.473	35.984–101.63	0.000	4.339	2.171–8.671	0.000
	With MDD, 1–2 yr	35.133	20.236–60.995	0.000	7.758	4.03–14.937	0.000
	With MDD, 3–5 yr	3.758	1.309–10.785	0.014	2.086	0.583–7.468	0.258
	With MDD, 6–10 yr	2.475	0.579–10.579	0.221	0.384	0.073–2.008	0.257
	With MDD, > 11 yr	1.291	0.349–4.784	0.702	0.283	0.072–1.109	0.070
Adjusted by		Age, gender			Age, gender, all other disorders

All other disorders: alcohol use disorder, eating disorder, obsessive-compulsive disorder, post-traumatic stress disorder, psychotic disorder, bipolar disorder, dysthymic disorder, social phobia, generalized anxiety disorder, specific phobia.

HR = hazard ratio, CI = confidence interval, MDD = major depressive disorder, PD = panic disorder.