Table 4. Summary of Differences in Blood Flow among Fenestrated and Completed Fontan Circulation Groups Compared to Controls.
Group 1: Fenestrated Fontan, MR under GA (n = 15) | Group 2: Completed Fontan, MR under GA (n = 6) | Group 3: Completed Fontan, MR without GA (n = 18) | |
---|---|---|---|
Age at MR (year) | 5.90 ± 2.84 | 8.70 ± 4.89 | 12.50 ± 3.42 |
Cardiacoutput | Marginally ↑ (1.05) | Marginally ↓ (0.85) | Mildly ↓ (0.82) |
Superior vena cava | Marginally ↑ (1.07) | Marginally ↓ (0.89) | Mildly ↓ (0.75) |
Fontan flow | Markedly ↓ (0.39) | Markedly ↓ (0.40) | Moderately ↓ (0.65) |
AP collaterals | 34% of cardiac output | 22% of cardiac output | 14% of cardiac output |
Abdominal aortic blood flow | Moderately ↓ (0.56) | Mildly ↓ (0.81) | Moderately ↓ (0.67) |
Celiac axis flow | Moderately ↓ (0.52) | Markedly ↓ (0.46) | Mildly ↓ (0.78) |
SMA flow | Moderately ↓ (0.67) | Marginally ↓ (0.92) | Markedly ↓ (0.31) |
SMV flow | Moderately ↓ (0.63) | Mildly ↓ (0.71) | Markedly ↓ (0.26) |
Portal venous flow | Moderately ↓ (0.53) | Moderately ↓ (0.59) | Markedly ↓ (0.37) |
Hepatic arterial flow | Markedly ↓ (0.32) | Markedly ↓ (0.21) | Markedly ↑* |
Hepatic venous flow | Markedly ↓ (0.33) | Markedly ↓ (0.42) | Moderately ↓ (0.72) |
Hepatic arterial contribution to hepatic venous flow | 33% (20% in control group in fasting status) | 17% (20% in control group in fasting status) | 45% (no significant flow in control group after meal) |
Renal blood flow | Markedly ↓ (0.34) | Markedly ↓ (0.46) | Moderately ↓ (0.69) |
Aortic bifurcation | Markedly ↓ (0.39) | Markedly ↓ (0.35) | Mildly ↓ (0.81) |
Numbers in parentheses are ratios between flow volumes of patients and healthy control groups. Decreased blood flow volume was graded mildly, moderately and markedly when ratio was > 0.75, 0.50–0.75, and < 0.50, respectively. When difference did not reach statistical significance, it was described as ‘marginally.’ *As hepatic arterial flow is normally negligible after meal, flow ratio between patients and healthy controls is not applicable. ↑ = increased, ↓ = decreased