Table 2.
Comparison of pretreatment characteristics between patients with acute myeloid leukemia with typical and those with atypical complex karyotype
| Characteristic | Atypical CK n=40 | Typical CK n=96 | P-valuea |
|---|---|---|---|
| Age, years | 0.007 | ||
| Median | 53 | 59 | |
| Range | 18-77 | 30-84 | |
| Sex, n (%) | 0.23 | ||
| Male | 30 (75) | 61 (64) | |
| Female | 10 (25) | 35 (36) | |
| Race, n (%) | 0.78 | ||
| White | 34 (85) | 79 (88) | |
| Non-white | 6 (15) | 11 (12) | |
| Hemoglobin, g/dl | 0.14 | ||
| Median | 9.5 | 9.0 | |
| Range | 5.5-14.4 | 6.0-14.7 | |
| Platelet count, ×109/l | 0.96 | ||
| Median | 54 | 49 | |
| Range | 6-376 | 4-323 | |
| WBC count, ×109/l | 0.001 | ||
| Median | 23.8 | 6.0 | |
| Range | 0.8-225.3 | 0.7-137.6 | |
| Bone marrow blasts, % | <0.001 | ||
| Median | 76 | 46 | |
| Range | 20-92 | 13-97 | |
| Blood blasts, % | 0.006 | ||
| Median | 59 | 28 | |
| Range | 0-98 | 0-99 | |
| Extramedullary involvement, n (%) | 9 (24) | 10 (11) | 0.06 |
| Number of chromosome abnormalities | <0.001 | ||
| Median | 4 | 9 | |
| Range | 3-15 | 3-33 | |
Abbreviations: CK, complex karyotype; WBC, white blood cell.
a
P-values for categorical variables are from Fisher’s exact test, P-values for continuous variables are from Wilcoxon rank sum test.