Table 3.
Logistic regression of BMI genetic risk score (clumping at r2 cutoff .1 and 250 kb window including 10 PCs at p<1.0) as predictor and weight gain goals and behaviors as outcomes
Females | Males | |||||
---|---|---|---|---|---|---|
OR (95% CI) | p | pseudo R2 | OR (95% CI) | p | pseudo R2 | |
Weight gain goals | 0.59 (0.46–0.75) | <0.001 | 0.03 | 0.80 (0.72–0.89) | <0.001 | 0.01 |
Weight gain behaviorsa | 0.59 (0.45–0.77) | <0.001 | 0.03 | 0.79 (0.70–0.88) | <0.001 | 0.02 |
Adjusted for BMIb | ||||||
Weight gain goals | 0.76 (0.58–1.00) | 0.05 | 0.17 | 1.02 (0.91–1.14) | 0.76 | 0.09 |
Weight gain behaviorsa | 0.76 (0.57–1.02) | 0.07 | 0.17 | 1.03 (0.91–1.18) | 0.63 | 0.12 |
Bold indicates p<0.00625 (Bonferroni correction)
Weight gain behaviors include eating more, eating different foods than normal, and taking food supplements to gain weight
BMI is significantly associated with all outcomes in both sexes (p<0.001)