Table 4.
Application of the Machine-Learning Coded-only, Second Case Definition SLE Algorithm (Algorithm 2) to an External Validation Cohort at Vanderbilt University Medical Center
| Outcome: Definite/Probable SLE vs. Non-SLE | ||
|---|---|---|
| Specificity (%) | Sensitivity (%) | PPV (%) |
| 100 | 25 | 100 |
| 98 | 42 | 95 |
| 97 | 61 | 94 |
| 96 | 63 | 93 |
External cohort includes 173 randomly selected subjects at Vanderbilt University Medical Center with ≥ 1 ICD-9 code for SLE after the year 2000. SLE case definition= specialist-reported SLE diagnosis.