TABLE 2.
Comparison of patients with and those without VTE
| Variable | No VTE (n = 1574) | VTE (n = 48) | p Value |
|---|---|---|---|
| Age in yrs, mean (SD) | 52.7 (15.9) | 60.1 (11.9) | 0.001 |
| Range | (18–89) | (33–79) | |
| Sex | |||
| Male | 743 (47.2) | 22 (45.8) | |
| Female | 831 (52.8) | 26 (54.2) | 0.341 |
| BMI in kg/m2 | 28.8 (6.2) | 29.7 (6.5) | 0.353 |
| Range | (14.6–59.8) | (20.7–47.8) | |
| History of VTE | |||
| No | 1534 (97.5) | 38 (79.2) | |
| Yes | 40 (2.5) | 10 (20.2) | <0.001 |
| KPS score <80 | |||
| No | 1308 (83.1) | 33 (68.8) | |
| Yes | 266 (16.9) | 15 (31.2) | 0.001 |
| Pre- or postop motor deficit | |||
| No | 1268 (80.6) | 26 (54.2) | |
| Yes | 306 (19.4) | 22 (45.8) | <0.001 |
| Chronic steroid use | |||
| No | 1054 (67.0) | 24 (50.0) | |
| Yes | 520 (33.0) | 24 (50.0) | 0.014 |
| Preop antiplatelet use | |||
| No | 1254 (79.7) | 32 (66.7) | |
| Yes | 320 (20.3) | 16 (33.3) | 0.029 |
| Preop anticoagulation | |||
| No | 1518 (96.4) | 40 (83.3) | |
| Yes | 56 (3.6) | 8 (16.7) | <0.001 |
| Admission type | |||
| Elective | 1461 (92.8) | 41 (85.4) | |
| Nonelective | 113 (7.2) | 7 (14.6) | 0.054 |
| Revision craniotomy | |||
| No | 1267 (80.5) | 38 (79.2) | |
| Yes | 307 (19.5) | 10 (20.8) | 0.819 |
| Location | |||
| Supratentorial | 1325 (84.2) | 37 (77.1) | |
| Infratentorial | 249 (15.8) | 11 (22.9) | 0.189 |
| Intraaxial | 936 (59.5) | 27 (56.3) | |
| Extraaxial | 638 (40.5) | 21 (43.7) | 0.655 |
| Pathology | |||
| Glial-based tumor | 765 (48.6) | 19 (39.6) | |
| Schwannoma/meningioma | 554 (34.2) | 16 (33.3) | |
| Metastatic lesion | 102 (6.5) | 6 (12.5) | |
| Other | 153 (9.7) | 7 (14.6) | 0.214 |
| Pathological grade* | |||
| 1 | 554 (35.7) | 14 (29.2) | |
| 2 | 262 (16.9) | 8 (16.7) | |
| 3 | 240 (15.5) | 7 (14.6) | |
| 4 | 497 (32.0) | 19 (39.6) | 0.703 |
| Postop ICH | |||
| No | 1550 (98.5) | 42 (87.5) | |
| Yes | 24 (1.5) | 6 (12.5) | <0.001 |
| Prophylactic anticoagulation | |||
| No | 1398 (88.8) | 32 (66.7) | |
| Yes | 176 (11.2) | 16 (33.3) | <0.001 |
| Intubated >24 hrs/reintubated | |||
| No | 1523 (96.8) | 41 (85.4) | |
| Yes | 51 (3.2) | 7 (14.6) | <0.001 |
| LOS in days | 3.7 (4.3) | 7.0 (7.9) | <0.001 |
| Range | (1–119) | (1–46) | |
| Discharge location† | |||
| Home | 1271 (80.8) | 27 (56.3) | |
| Inpatient rehabilitation | 223 (14.2) | 17 (35.4) | |
| Skilled nursing facility | 78 (5.0) | 4 (8.3) | <0.001 |
Values are presented as number of patients (%) unless otherwise indicated.
Boldface type indicates statistical significance.
*
There were 21 lesions that were not assigned a pathological grade.
†
The 2 patients who died during their hospital admission were excluded from this analysis.