Table 1. Baseline demographics.
| Characteristic | No. (%) (n=267) |
|---|---|
| Age, median (range), yr | 64 (24–82) |
| Sex | |
| Male | 191 (71.5) |
| Female | 76 (28.5) |
| Smoking history | |
| Never | 87 (32.6) |
| Former | 83 (31.3) |
| Current | 97 (36.3) |
| Histologic type | |
| Adenocarcinoma | 185 (69.3) |
| Squamous cell carcinoma | 73 (27.7) |
| Others* | 8 (3) |
| Biopsy method | |
| Operation | 71 (26.6) |
| Small biopsy† | 192 (71.9) |
| Cytology | 4 (1.5) |
| Histologic grade | |
| Well differentiated | 54 (20.2) |
| Moderately differentiated | 76 (28.5) |
| Poorly differentiated | 74 (27.7) |
| Others‡ | 23 (8.6) |
| EGFR mutation | |
| Wild type | 153 (57.3) |
| Mutated | 65 (24.3) |
| Not checked | 58 (17.6) |
| ALK FISH | |
| Negative | 93 (34.8) |
| Positive | 17 (6.4) |
| Not checked | 157 (58.8) |
*Other types consisting of small cell lung cancer (5 cases) and large cell lung cancer (3 cases). †Small biopsy specimens were collected via bronchoscopy, endobronchial ultrasound-transbronchial needle aspiration, or transthoracic needle biopsy of the lung. ‡“Others” included specimens for which histologic grade could not be checked.
EGFR: epidermal growth factor receptor; ALK: anaplastic lymphoma kinase; FISH: fluorescence in situ hybridization.