Figure 2.
Effect of CCK‐8 on adiponectin and PPARγ gene expression. Effect of acute and chronic administration of CCK‐8 (10 μg·kg−1) on adiponectin (Adipoq) and PPARγ gene (Pparg) expression in subcutaneous (a, b) and visceral WAT (c, e). The effect of CCK‐8 was also assayed in pre‐adipocytes. Panels (e) and (g) show the effect of CCK‐8 on Adipoq expression in subcutaneous and visceral pre‐adipocytes. Panels (f) and (h) illustrate the effect of CCK‐8 on Pparg expression in subcutaneous and visceral pre‐adipocytes. Values are means ± SEM (n = 5 for acute in vivo, n = 6 for chronic in vivo, and n = 6 for in vitro assays). *P < .05, significantly different from their respective controls; ANOVA with Bonferroni's test