Levy 1992.

Methods	Study design: cross‐over RCT Follow‐up period: 15 weeks Duration of study: not reported
Participants	Country: USA Setting: single centre Inclusion criteria: clinically stable on chronic HD; high quality echocardiograms; in sinus rhythm Enrolled: 6 Mean age ± SD: 55 ± 11 years Sex (M/F): 6/0 Exclusion criteria: not reported
Interventions	Treatment arm Dialysate temperature of 35°C Control arm Dialysate temperature of 37°C
Outcomes	IDH rate Mean BP at end of HD
Notes	Funding source: not reported We requested further information but there was no response
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote "The dialysis procedures were performed in random order..."; method of randomisation was not reported
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) All outcomes	High risk	Blinding was not feasible because of the nature of the intervention
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Insufficient information to permit judgement
Incomplete outcome data (attrition bias) All outcomes	Low risk	No description about the first phase data including missing values but there were no dropouts
Selective reporting (reporting bias)	Unclear risk	The protocol was not available
Other bias	High risk	Carry‐over effects potentially existed. No description for the assessment of the baseline imbalance of first period of the cross‐over study