Table 4. Adverse reaction of rats with T2DM among different dosage of ATV groups.
Groups | n | Mental disorder | Vomit | Hyperspasmia | Sudden death | Incidence |
---|---|---|---|---|---|---|
Diabetes | 30 | 2 | 1 | 0 | 1 | 13.3% |
10 mg/kg/day | 20 | 2 | 1 | 0 | 0 | 15.0% |
20 mg/kg/day | 20 | 2 | 1 | 1 | 0 | 20.0% |
40 mg/kg/day | 20 | 2 | 1 | 1 | 0 | 20.0% |
80 mg/kg/day | 20 | 3 | 2 | 2 | 1 | 40.0% |
Data were analyzed by χ2 test. Abbreviation: N, number of cases.