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. 2019 Jun 4;9(7):1223–1231. doi: 10.1002/2211-5463.12651

Figure 5.

Figure 5

Overexpression of TCTN2 improved neurological function in SCI rat model. SCI rat model was intrathecally injected with pcDNA (n = 6) or pcDNA‐TCTN2 (n = 6) vector. (A) BBB scoring was used to estimate the neurological function at 1, 6, 12, 24, and 48 h after SCI induction. (B) Forty‐eight hours later, the spinal tissue of mice was taken and the expression of TCTN2 and miR‐216b in spinal tissue of rats was examined by qRT‐PCR. (C) The P62, LC3I, and LC3II protein level in spinal tissue was analyzed with western blot 48 h after SCI. *P < 0.05 compared with pcDNA. The error bars indicate SD. The experiments were repeated three times. Comparisons between the two groups were analyzed with Student's t test.